The aim of this study is to illuminate how hermeneutical interpretation at different levels moves in a circle from empirical findings toward a theoretical model. The methodology is inspired by Gadamer’s hermeneutical approach. The theoretical model builds on four substudies of nurses’ perspectives in end-of-life care. The material was obtained from a clinical context through individual and focus group interviews. The hermeneutical interpretation in the study moves from an empirical understanding of what a nurse does in caring and what it is like to be a nurse to the interpretation of the empirical assumptions in dialogue with selected texts from Kierkegaard.