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Physical fitness after myocardial infarction compared with clinical reference values: a SWEDEHEART registry study
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, (SWE); Physiotherapy Department, Region Västernorrland, Sundsvall (SWE).ORCID iD: 0009-0000-6456-7231
Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping (SWE); Clinical Department of Clinical Physiology, Region Östergötland, Linköping (SWE).ORCID iD: 0000-0001-9196-7820
Uppsala Clinical Research Center, Uppsala University, Uppsala (SWE).
Department of Medical Sciences, Cardiology, Uppsala University, Uppsala (SWE).
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2026 (English)In: Open heart, E-ISSN 2053-3624, Vol. 13, no 1, article id e004046Article in journal (Refereed) Published
Abstract [en]

Purpose The primary aim of this study was to describe physical fitness in a large real-world cohort of patients entering exercise-based cardiac rehabilitation (EBCR) after first-time myocardial infarction (MI). The secondary aim was to compare the results with clinical reference values.

Methods This registry-based cohort study used data from the Swedish Web-system for Enhancement and Development of Evidence-based care in Heart Disease Evaluated According to Recommended Therapies (SWEDEHEART) post-MI registry between 2016 and 2019. Patients with first-time MI who underwent physiotherapist-led assessments of physical fitness at EBCR entry were included. Exercise capacity was evaluated by a symptom-limited cycle ergometer test and muscular endurance by a unilateral heel-rise test. Results were compared with age-stratified and sex-stratified clinical reference values. Reference values for exercise capacity were based on the Swedish Kalmar dataset, the national standard reference in Sweden since 2014, and reference values for heel-rise performance were based on a Swedish normative dataset of healthy adults.

Results A total of 15 105 patients (mean age 62.5±9.1 years, 78.4% men) were included. Exercise capacity (Watt max from the exercise test) was higher in men than women across age groups, and muscular endurance declined with age, with a steeper age-related decline in women’s heel rise performance. The mean exercise capacity of the study population corresponded to 64.7±27.4% of predicted values in men and 68.4±18.9% in women. Muscular endurance averaged 78.4%±51.0% of reference values in men and 61.7%±43.2% in women.

Conclusion At EBCR entry after a first-time MI, both exercise capacity and muscular endurance were substantially below age-specific and sex-specific reference values. These results underscore the importance of systematic baseline assessments and tailored rehabilitation interventions targeting both exercise capacity and muscular endurance.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2026. Vol. 13, no 1, article id e004046
National Category
Cardiology and Cardiovascular Disease Physiotherapy
Research subject
NURSING AND PUBLIC HEALTH SCIENCE, Nursing science
Identifiers
URN: urn:nbn:se:hv:diva-25280DOI: 10.1136/openhrt-2026-004046ISI: 001775134700001Scopus ID: 2-s2.0-105039558206OAI: oai:DiVA.org:hv-25280DiVA, id: diva2:2062343
Funder
The Kamprad Family Foundation, 20190122Swedish Research Council, 2018-02794Forte, Swedish Research Council for Health, Working Life and Welfare, 2019-00422Swedish Heart Lung Foundation, 20200930Swedish Heart Lung Foundation, 20220305Region Västernorrland, LVNFOU1011367
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CC-BY-NC 4.0

Available from: 2026-05-25 Created: 2026-05-25 Last updated: 2026-06-02

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Åhlund, Kristina

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