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  • 1. Andersson, J E
    et al.
    Hansson, T
    Samuelson, Gösta
    Invagination och salmonellos - epidemiologiska synpunkter: [Invagination and salmonella--epidemiological viewpoints].1978In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 75, no 32-33, article id 2797Article in journal (Refereed)
  • 2. Arvidsson Lenner, R
    et al.
    Carlgren, G
    Carlgren, G
    Hardell, LI
    Johansson, B
    Jonsson, G
    Samuelson, Gösta
    Sandström, B
    Food and nutrient intake in Swedish diabetic children1989In: Näringsforskning, Vol. 33, no 4, p. 149-53Article in journal (Other academic)
  • 3. Asp, NG
    et al.
    Hallberg, L
    Hallmans, G
    Samuelson, Gösta
    Reutersvärd, AL
    Iron nutrition in health and disease: Referat från ett internationellt symposium1996In: Scandinavian Journal of Nutrition, ISSN 1102-6489, Vol. 40, no 2, p. 76-80Article in journal (Refereed)
  • 4. Axelsson, I
    et al.
    Gebre-Medhin, M
    Hernell, O
    Jakobsonn, I
    Michaelsen, K F
    Samuelson, Gösta
    [Recommendations for prevention of iron deficiency. Delay cow's milk intake as a beverage to infants until 10-12 months of age!].: Rekommendationer för att förebygga järnbrist. Vänta med komjölk som dryck tills barnet är 10-12 månader!1999In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 96, no 18, p. 2206-8Article in journal (Refereed)
    Abstract [sv]

    Breast-feeding is to be encouraged during the first six months of life. Iron deficiency is extremely rare in exclusively breast-fed infants during this period. Any cow-milk based formula used should be iron-fortified. During the second half of infancy, the iron content of weaning foods is important in preventing iron deficiency. Indeed, owing to the low iron content of dairy products, it is hard to compose a weaning diet sufficiently rich in iron to meet the demands of rapidly growing infants, if it is to include substantial amounts of cow milk, sour milk or yoghurt. Accordingly, the Paediatric Committee on Nutrition and Health, of the Swedish Paediatric Association and the National Food Administration, recommend delaying the introduction of cow's milk and cow-milk products until the infant is 10-12 months of age. Until then, breast-feeding, and the use of iron-fortified formula or gruel with modified protein and sodium content are encouraged; iron-fortified porridges of softer consistency can be prepared to circumvent the need of extra fluids, or porridge can be served with breast milk or iron-fortified formula; small amounts of milk may be used for cooking purposes.

  • 5. Axelsson, I
    et al.
    Gebre-Medhin, M
    Hernell, O
    Jakobsson, I
    Michaelsen, K F
    Samuelson, Gösta
    [A reply about milk porridge. Infant food is also a question of nutritional physiology].: Replik om mjölk på gröten. Spädbarns kost också en näringsfysiologiskfråga1999In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 96, no 21, p. 2624-5Article in journal (Refereed)
  • 6. Axelsson, I
    et al.
    Gebre-Medhin, M
    Hernell, O
    Jakobsson, I
    Michaelsen, K F
    Samuelson, Gösta
    [The AD-drops can be replaced by D-drops].: AD-dropparna kan ersättas med D-droppar1999In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 96, no 18, p. 2200-4Article in journal (Refereed)
    Abstract [sv]

    Since 1932, when vitamin A and D supplementation, in the form of cod liver oil, was introduced in Sweden, rickets has been a rare diagnosis among Swedish infants. In 1978, the National Board of Health and Welfare issued recommendations of daily supplementation with 300 micrograms (1000 IU) of vitamin A and 10 micrograms (400 IU) of vitamin D. This has recently been under review by the Paediatric Committee on Nutrition and Health, of the Swedish Paediatric Association and the National Food Administration, who concluded that there is no reason to retain vitamin A supplementation, but that vitamin D supplementation should continue to be recommended at the same daily dose (400 IU).

  • 7. Axrup, K
    et al.
    Lindqvist, B
    Samuelson, Gösta
    Oral-facial-digital syndrome. A case report1971In: Odontologisk revy, ISSN 0029-8441, Vol. 22, no 2, p. 137-44Article in journal (Refereed)
  • 8. Bergfors, P G
    et al.
    Höglund, T
    Samuelson, Gösta
    Winberg, J
    Lasarettsvecka i pediatrik : Försöksverksamhet  under grundutbildningen: [Hospital week in pediatricsExperiments in medical education].1974In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 71, no 22, p. 2237-8Article in journal (Refereed)
  • 9. Bjure, J
    et al.
    Fälström, S P
    Latuszek, B
    Samuelson, Gösta
    Cystisk fibros med okaraktäristisk debut: [Cystic fibrosis with uncharacteristic onset].1976In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 73, no 10, article id 870Article in journal (Refereed)
  • 10. Brattby, LE
    et al.
    Sandhagen, B
    Enghardt, H
    Fan, H
    Samuelson, Gösta
    Validering av ungdomars kostintag1998In: Scandinavian Journal of Nutrition/Næringsforskning, ISSN 1102-6480, E-ISSN 1651-2359, Vol. 42, no 1, p. 29-30Article in journal (Refereed)
  • 11. Brattby, LE
    et al.
    Sandhagen, B
    Samuelson, Gösta
    Energiförbrukning, fysisk aktivitet och idrottsvanor hos 15-åringar i Uppsala och Trollhättan1998In: Scandinavian Journal of Nutrition, ISSN 1102-6489, Vol. 42, no 1, p. 31-34Article in journal (Refereed)
  • 12. Bratteby, L E
    et al.
    Samuelson, Gösta
    Sandhagen, B
    Mallmin, H
    Lantz, H
    Sjöström, L
    Whole-body mineral measurements in Swedish adolescents at 17 years compared to 15 years of age.2002In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 91, no 10, p. 1031-8Article in journal (Refereed)
    Abstract [en]

    AIM: To provide reference data for bone mineral variables in 15- and 17-y-old adolescents and to analyse the relationships between these variables and measures of bone and body size, gender, puberty, growth, various lifestyle and environmental factors and socioeconomic background.

    METHODS: In the same 321 randomly selected adolescents (147 boys and 174 girls) living in two different regions of Sweden, the total bone mineral content (TBMC), bone area (BA) and total bone mineral density (TBMD) were assessed by dual-energy X-ray absorptiometry at ages 15 and 17 y. The effects of bone and body size, gender, growth, sexual maturity, physical activity, region of domicile, social conditions, food habits, smoking and alcohol intake on TBMC and TBMD were examined in multivariate analyses.

    RESULTS: In the 15-y-old adolescents, BA, height, gender, physical activity, maturity and weight explained 91% and 48%, of the variance in TBMC and TBMD, respectively. In similar analyses in the 17-y-olds, the corresponding figures were 92% and 62%, respectively, when BA, height, growth, physical activity, gender and region emerged as significant in the model. In all these analyses, BA explained most of the variance in TBMC and TBMD. No significant reduction of variance was found when different measures of social conditions, smoking, food habits, alcohol or dietary intakes of energy, calcium or vitamin D were included in the models. The reason why region of domicile had a significant impact on TBMC in the 17-y-olds is not known. The fact that the normal fluoride concentration in drinking water (1.1 mg/L) is 10 times higher in the region where TBMC was higher than in the other region is an interesting observation.

    CONCLUSION: Almost 90% of the variance in TBMC and 50% of that in TBMD was explained by measures of bone and body size and only a few percent by gender, physical activity, Tanner stage, growth and region of domicile.

  • 13. Bratteby, L E
    et al.
    Sandhagen, B
    Fan, H
    Enghardt, H
    Samuelson, Gösta
    Total energy expenditure and physical activity as assessed by the doubly labeled water method in Swedish adolescents in whom energy intake was underestimated by 7-d diet records.1998In: American Journal of Clinical Nutrition, ISSN 0002-9165, E-ISSN 1938-3207, Vol. 67, no 5, p. 905-11Article in journal (Refereed)
    Abstract [en]

    Swedish children and adolescents may be adopting a sedentary lifestyle with low energy expenditures and intakes, but no quantitative data are available. The purpose of the present study in 50 adolescents aged 15 y was to investigate whether assessment of total energy expenditure (TEE) and physical activity level (PAL) by the doubly labeled water method and indirect calorimetry and estimation of energy intake by a 7-d diet record would indicate physical inactivity. The boys' (n = 25) mean weight was 112% and the girls' (n = 25) was 109% of Swedish reference values from 1976; the mean height of both boys and girls was 102% of those reference values. Mean TEE in the boys and girls, 13.82 +/- 1.90 and 10.70 +/- 1.59 MJ/d, and mean PAL (TEE/basal metabolic rate), 1.89 +/- 0.16 and 1.79 +/- 0.22, respectively, were nonsignificantly higher than corresponding figures from other published studies. Mean energy intake as a percentage of TEE was 81.9 +/- 17.9% in the boys and 78.3 +/- 16.4% in the girls. Significant negative correlations were found both between energy intake as a percentage of TEE and percentage body fat and between energy intake as a percentage of TEE and body mass index. These results add to the evidence that 7-d diet records underestimate energy intake in adolescents, particularly those with a tendency for overweight and increased body fat. The results support indications of a trend of increasing body weight and height in Swedish adolescents, but conflict with the presumptions of low physical activity, low energy expenditure, and low energy intake. These results support the view that current recommendations for energy intake during adolescence are too low.

  • 14. Bratteby, L E
    et al.
    Sandhagen, B
    Fan, H
    Samuelson, Gösta
    A 7-day activity diary for assessment of daily energy expenditure validated by the doubly labelled water method in adolescents.1997In: European Journal of Clinical Nutrition, ISSN 0954-3007, E-ISSN 1476-5640, Vol. 51, no 9, p. 585-91Article in journal (Refereed)
    Abstract [en]

    OBJECTIVES: To validate the use of an activity diary and predicted BMR for assessment of daily total energy expenditure (TEE) and physical activity level (PAL = TEE/BMR) in adolescents.

    DESIGN: TEE and PAL estimated from activity diary records kept for seven days and BMR predicted from age, gender and body weight were compared with the results of doubly labelled water (DLW) measurements and indirect calorimetry performed during the same time period.

    SETTING: The Unit of paediatric Physiology of the Department of Clinical Physiology, University Hospital, Uppsala, Sweden.

    SUBJECTS: Fifty randomly selected 15 y old adolescents (25 boys and 25 girls).

    RESULTS: The mean difference between TEE estimated in all adolescents by the activity diary and by DLW methods was 1.2%. The limits of agreement (mean difference 2 s.d.) were -3.47 and 3.77 MD/d, equivalent to a coefficient of variation of 15%. The mean difference between PAL assessed by activity diary records and by DLW measurements was 0.001, and the limits of agreement between the two methods were 0.54.

    CONCLUSIONS: The results imply that the activity diary method provides a close estimate of TEE and PAL in population groups.

  • 15. Bratteby, L E
    et al.
    Sandhagen, B
    Lötborn, M
    Samuelson, Gösta
    University West, Department of Health Sciences, Section for nursing - graduate level.
    Daily energy expenditure and physical activity assessed by an activity diary in 374 randomly selected 15-year-old adolescents.1997In: European Journal of Clinical Nutrition, ISSN 0954-3007, E-ISSN 1476-5640, Vol. 51, no 9, p. 592-600Article in journal (Refereed)
    Abstract [en]

    OBJECTIVES: To assess the average daily levels of physical activity, energy expenditure and the time and energy spent a different activities in two cohorts of Swedish adolescents.

    DESIGN: Total energy expenditure (TEE) and physical activity level (PAL = TEE/basal metabolic rate (BMR)) were estimated in 374 randomly selected healthy adolescents living with two different regions of Sweden on the basis of a seven-day activity diary (AD) and predicted BMR. A validation of the estimates from the AD with the doubly labelled water (DLW) method in a randomly selected subsample of 50 of these subjects is presented elsewhere.

    SETTING: The Unit of Paediatric of the Department of Clinical Physiology, University Hospital, Uppsala and the Department of Paediatrics, Northern Alvsborg Hospital, Trollhättan, Sweden.

    RESULTS: No significant differences in TEE and PAL were found between the adolescents of the two regions. High levels of TEE (14.2 and 10.9 MJ/d in boys and girls, respectively) and PAL (1.95 and 1.80) were observed. There was a close association between the PAL and the adolescents and their reported time spent sitting. Those with the lowest PAL values spent 3-6 h longer each day sitting compared to those with the highest PAL values. The results also indicate that everyday activities such as walking and bicycling have a crucial impact on the PAL values.

    CONCLUSIONS: In the 15 y old adolescents of the two studied regions of Sweden, high and concordant levels of energy expenditure and physical activity were found.

  • 16. Bratteby, L-E
    et al.
    Samuelson, Gösta
    University West, Department of Health Sciences, Section for nursing - graduate level.
    Tid ägnad olika aktivitetstyper hos ungdomar med varierande grad av fysisk aktivetet1997Conference paper (Other academic)
  • 17.
    Bratteby, L-E
    et al.
    University Hospital, Department of Medical Sciences, Clinical Physiology.
    Sandhagen, B
    Hospital, Department of Medical Sciences, Clinical Physiology.
    Samuelson, Gösta
    University West, Department of Nursing, Health and Culture, Division of Advanced Nursing.
    Physical activity, energy expenditure and their correlates in two cohorts of Swedish subjects between adolescence and early adulthood2005In: European Journal of Clinical Nutrition, ISSN 0954-3007, E-ISSN 1476-5640, Vol. 59, no 11, p. 1324-34Article in journal (Refereed)
    Abstract [en]

    OBJECTIVE: To assess physical activity and energy expenditure and to identify their correlates during adolescence and early adulthood. DESIGN: In a cohort study, total energy expenditure (TEE) and physical activity level (PAL) were assessed at 15 and 21 y from a 7-day activity diary and predicted BMR. The influences on TEE and PAL of body size, gender, sexual maturity, physical activity habits, sitting time, region, social conditions, employment, food habits, smoking and alcohol intake were examined in multivariate analyses.Subjects:71 male and 89 female subjects, living in two socioeconomically different regions of Sweden, a university region and an industrial region. SETTING: The university city of Uppsala and the industrial town of Trollhättan. RESULTS: At both 15 and 21 y, PAL and TEE were high, with gender, sitting time and physical activity habits as main correlates. At age 21 y, employment and the mother's educational level also appeared as significant correlates. The relations between the main variables and their correlates were more complex than at age 15 y, and the sitting time was reduced and the activity habits were changed. CONCLUSIONS: A reduction of daily sitting appears to be a major reason why high levels of physical activity and energy expenditure were maintained from 15 to 21 y of age in spite of changed and less frequent activity habits during this interval.

  • 18. Bruce, Å
    et al.
    Hagman, U
    Persson, LÅ
    Samuelson, Gösta
    Sjölin, S
    Näringsintag hos svenska barn: Resultat från en multicenter studie 1980-19811984In: Vår föda, ISSN 0042-2657, Vol. 36, no suppl 2, p. 61-134Article in journal (Other academic)
  • 19. Bruce, Åke
    et al.
    Eriksson, HB
    Samuelson, Gösta
    Sjölin, S
    Svenska barns kost och hälsa: data n från en multicenterstudie 1980-1981. V. Intag av energigivande näringsämnen.1983Conference paper (Other academic)
  • 20. Bruce, Åke
    et al.
    Hagman, U
    Persson, LÅ
    Samuelson, Gösta
    Sjölin, S
    Näringsintag hos svenska barn: resultat från en multicenterstudie 1980-1981. Sammanfattning av supplement nr 2, 1984 - och nya data.1984In: Vår föda, ISSN 0346-7341, Vol. 36, no 6-7, p. 317-324Article in journal (Other academic)
  • 21. Bruce, Åke
    et al.
    Hagman, U
    Persson, LÅ
    Samuelson, Gösta
    Sjölin, S
    Svenska barns kost och hälsa: presentation från en multicenterstudie 1980-1981. I. Syfte, material och metodik1982Conference paper (Other academic)
  • 22. Bárány, E
    et al.
    Bergdahl, I A
    Bratteby, L-E
    Lundh, T
    Samuelson, Gösta
    Skerfving, S
    Oskarsson, A
    Iron status influences trace element levels in human blood and serum.2005In: Environmental Research, ISSN 0013-9351, E-ISSN 1096-0953, Vol. 98, no 2, p. 215-23Article in journal (Refereed)
    Abstract [en]

    Food is the main source of trace elements for the general population. The gastrointestinal absorption of certain trace elements, e.g., cadmium, is strongly influenced by iron (Fe) status. This factor may also be relevant for the bioavailability of other trace elements. Therefore, we investigated relationships between Fe status indicators and trace element concentrations in blood and serum of 234 boys and girls at ages 15 and 17 years. Fe status was measured using serum ferritin (S-Ft), soluble transferrin receptor in serum (sTfR), and the ratio sTfR/S-Ft. The trace elements we investigated were, in blood, cadmium, cobalt, copper, zinc, selenium, rubidium, mercury, and lead, and, in serum, cobalt, copper, zinc, selenium, rubidium, tungsten, mercury, and lead. We found inverse correlations between Fe status and blood cadmium, blood or serum cobalt, or blood copper. There were positive correlations between Fe status and mercury concentrations. Selenium was positively correlated with sTfR. The relationships between Fe status and lead were equivocal. There were fewer correlations for serum than for blood, but the inverse relationships between Fe status and cobalt were equally strong in serum and blood. We found only occasional, and perhaps spurious, correlations with zinc, rubidium, and tungsten. In conclusion, previous indications that cadmium, cobalt, and copper are absorbed by transport mechanisms similar to that of Fe are supported by this study. Strong positive correlations between Fe status and mercury concentrations remain to be explained.

  • 23. Bárány, Ebba
    et al.
    Bergdahl, Ingvar A
    Bratteby, Lars-Eric
    Lundh, Thomas
    Samuelson, Gösta
    Schütz, Andrejs
    Skerfving, Staffan
    Oskarsson, Agneta
    Trace element levels in whole blood and serum from Swedish adolescents.2002In: Science of the Total Environment, ISSN 0048-9697, E-ISSN 1879-1026, Vol. 286, no 1-3, p. 129-41Article in journal (Refereed)
    Abstract [en]

    Blood and serum samples from 372 15-year-old adolescents were collected in two cities in Sweden and analyzed by inductively coupled plasma mass spectrometry (ICP-MS). The objective was to (1) determine the levels of 13 elements in blood and serum from the teenagers; and (2) for each element, investigate the correlation between the concentrations in blood and serum. The concentrations in blood and serum were generally in line with that usually reported for the essential elements Co, Cu, Zn and Se, and generally low for the 'non-essential' elements Cd, Hg, Pb. The median concentrations were in blood and serum, respectively: of Co 0.31 and 0.48 microg/l, Cu 0.92 and 1.0 mg/l, Zn 6.1 and 0.99 mg/l, Se 110 and 100 microg/l, Rb 2.8 and 0.24 mg/l, Hg 1.1 and 0.44 microg/l, Pb 16 and 0.33 microg/l. The median concentration of W in blood was <0.2 microg/l (below the detection limit) and in serum 0.087 microg/l. The median concentrations of Cd, Rh, Pd, Pt and Tl were below the detection limits. Statistically significant correlations were found between the concentrations in blood and serum for Co, Cu, Zn, Se, Rb, W, Hg and Pb. The levels presented in this study constitute baseline levels or levels generally not exceeded in adolescents for 13 elements, including essential, ubiquitous toxic, and rare elements.

  • 24. Bárány, Ebba
    et al.
    Bergdahl, Ingvar A
    Bratteby, Lars-Eric
    Lundh, Thomas
    Samuelson, Gösta
    Schütz, Andrejs
    Skerfving, Staffan
    Oskarsson, Agneta
    Trace elements in blood and serum of Swedish adolescents: relation to gender, age, residential area, and socioeconomic status.2002In: Environmental Research, ISSN 0013-9351, E-ISSN 1096-0953, Vol. 89, no 1, p. 72-84Article in journal (Refereed)
    Abstract [en]

    The influence of gender, age, residential area, and socioeconomic status on the blood and serum levels of 13 trace elements was studied in boys and girls living in two Swedish cities with different socioeconomic and environmental characters. The same groups of adolescents were sampled twice, at ages 15 (n=372) and 17 (n=294) years. All the investigated factors were shown to be of importance. Age was important for most elements; e.g., copper levels in both blood and serum increased in girls, and selenium increased in serum from both genders. Lead decreased approximately 10% in blood from the first to the second sampling, and cadmium increased in blood, however not in nonsmokers. The age factor may also reflect temporal changes in environmental exposure, especially for nonessential elements. Girls had higher levels of cobalt and copper, while lead in blood was higher in boys. Smoking girls had higher copper levels than nonsmoking girls. Residential area influenced all elements. The teenagers with university-educated mothers had higher levels of cadmium in blood than those with only primary school-educated mothers.

  • 25. Bárány, Ebba
    et al.
    Bergdahl, Ingvar A
    Bratteby, Lars-Eric
    Lundh, Thomas
    Samuelson, Gösta
    Skerfving, Staffan
    Oskarsson, Agneta
    Mercury and selenium in whole blood and serum in relation to fish consumption and amalgam fillings in adolescents.2003In: Journal of Trace Elements in Medicine and Biology, ISSN 0946-672X, E-ISSN 1878-3252, Vol. 17, no 3, p. 165-70Article in journal (Refereed)
    Abstract [en]

    Mercury and selenium in whole blood and serum of 245 17-year old Swedish adolescents were analysed. The relationships between these elements' concentrations and the consumption of fish as well as the number of dental amalgam fillings were studied. The geometric means (GM) of the mercury concentrations were 1.1 microg/L in blood and 0.43 microg/L in serum. The mean selenium concentration in blood was 110 microg/L and the GM of the serum selenium concentration 110 microg/L. Fish species with dietary restrictions due to elevated mercury Levels (i.e. pike, perch, pikeperch, burbot, eel and halibut) were consumed on average 0.7 times/month and fish species without such restrictions 4.1 times/month. Despite this comparatively low fish consumption, the adolescents' blood mercury concentrations were positively correlated with fish consumption. Of the adolescents, 39% had amalgam fillings (mean 2 +/- 1.5). Serum mercury was influenced by the number of amalgam fillings, by fish consumption, blood and serum levels of selenium and the residential area. Blood and serum selenium concentrations were not influenced by fish consumption, but were positively associated with the serum mercury concentration.

  • 26. Domellöf, L
    et al.
    Eriksson, S
    Samuelson, Gösta
    Sönne, B
    Local perineal actinomycosis1974In: Acta paediatrica Scandinavica, ISSN 0001-656X, Vol. 63, no 3, p. 450-2Article in journal (Refereed)
  • 27. Eksmyr, R
    et al.
    Fex, G
    Jagell, S
    Johansson, B G
    Ravnskov, U
    Samuelson, Gösta
    Low molecular weight proteinuria and slight hyperlipoproteinemia in three mentally retarded brothers.1976In: Acta paediatrica Scandinavica, ISSN 0001-656X, Vol. 65, no 4, p. 521-5Article in journal (Refereed)
    Abstract [en]

    Mental retardation in combination with proteinuria and a slight hyperlipoproteinemia was found in three brothers. The increased urinary protein excretion was dominated by albumin and the low molecular weight proteins retinol-binding protein (RBP) and beta2-microglobulin, indicating the presence of proximal tubular dysfunction. However, there was no glucosuria, phosphaturia or amino aciduria and the renal concentrating and acidification capacities were normal. A kidney biopsy in one of the patients revealed morphologic evidence of glomerular damage but a normal tubular structure. A mild hyper-beta-lipoproteinemia was found in the patients but not in their healthy siblings. The cause of this syndrome, hitherto not described, is unknown.

  • 28. Engelhardt, H
    et al.
    Hedgren, M
    Amcoff, B
    Robinson, J
    Bratteby, LE
    Samuelson, Gösta
    En förberedande koststudie inför projektet: Ungdom mot år 20001994In: Vår föda, ISSN 0042-2657, Vol. 46, no 2, p. 78-87Article in journal (Other academic)
  • 29. Engelhardt, H
    et al.
    Hedgren, M
    Amcoff, B
    Robinson, J
    Bratteby, LE
    Samuelson, Gösta
    En förberedande koststudie inför projektet: Ungdom mot år 20001994In: Elevvård & Hälsa, ISSN 1102-3120, no 2, p. 19-24Article in journal (Other academic)
  • 30. Enghardt, H
    et al.
    Hedgren, M
    Brattby, LE
    Samuelson, Gösta
    Kostvanor hos ungdomar i Trollhättan och Uppsala: "Ungdom mot år 2000"1998In: Scandinavian Journal of Nutrition, ISSN 1102-6489, Vol. 42, no 1, p. 21-24Article in journal (Refereed)
  • 31. Falkmer, S
    et al.
    Samuelson, Gösta
    Sjölin, S
    Penicillaminbehandling vid Wilsons sjukdom: [Penicillamine treatment of Wilson's disease].1969In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 66, no 20, p. 2097-105Article in journal (Refereed)
  • 32. Falkmer, S
    et al.
    Samuelson, Gösta
    Sjölin, S
    Penicillamine-induced normalization of clinical signs, and liver morphology and histochemistry in a case of Wilson's disease.1970In: Pediatrics, ISSN 0031-4005, E-ISSN 1098-4275, Vol. 45, no 2, p. 260-8Article in journal (Refereed)
  • 33. Fleischer Michaelsen, K
    et al.
    Sauer Larsen, P
    Lykke Thomsen, B
    Samuelson, Gösta
    Ammeperiodens laengde: hvilke faktorer har betydning1995In: Ugeskrift for læger, ISSN 0041-5782, E-ISSN 1603-6824, Vol. 157, no 16, p. 2311-2315Article in journal (Refereed)
  • 34. Gebre-Medhin, M
    et al.
    Samuelson, Gösta
    [Diet during childhood and adolescence can influence health even in adulthood].: Kost och hälsa: Kosten under barn- och ungdomsåren kan påverka hälsan även i vuxen ålder1990In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 87, no 46, p. 3881-6Article in journal (Refereed)
  • 35. Gustavson, K H
    et al.
    Samuelson, Gösta
    Söderberg, M
    [Congenital syphilis in adopted children from developing countries].1981In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 78, no 32-33, p. 2773-4Article in journal (Refereed)
  • 36. Hagman, U
    et al.
    Bruce, A
    Persson, L A
    Samuelson, Gösta
    Sjölin, S
    Food habits and nutrient intake in childhood in relation to health and socio-economic conditions. A Swedish Multicentre Study 1980-81.1986In: Acta paediatrica Scandinavica. Supplement, ISSN 0300-8843, Vol. 328, p. 1-56Article in journal (Refereed)
    Abstract [en]

    In Sweden a multicentre nutritional survey was performed in 1980-81 in four different parts of Sweden. The total number of children investigated was 1109, of whom 92 were two years old, 332 four years, 338 eight years and 347 thirteen years. The 24-hour recall method was used in all children. In addition 7-day record was used in the 2-, 4- and 8-year-olds and the dietary history method in the 13-year-olds. During the weekdays the 2-, 4-, 8- and 13-year-old children had 5.9, 5.8, 5.4 and 5.2 meals and snacks per day, respectively. During weekends these respective numbers decreased to 5.7, 5.6, 5.1 and 5.0. The mean number of light meals and snacks was almost the same on all days and varied between 2.4 and 3.3 in the different age groups. The part of the energy intake deriving from snacks has increased during the last 15 years. The mean daily energy intakes for the 2-, 4-, 8- and 13-year-old boys and girls were 5.8 and 5.6, 6.9 and 6.5, 8.9 and 7.9 and 12.1 and 9.7 MJ respectively. These values are below the recommendations for all age groups except the 2-year-old boys. The mean daily intakes of protein, retinol, ascorbic acid, thiamin, riboflavin, niacin, vitamin B12 and calcium were almost invariably higher or much higher than the recommendations, while those of vitamin D and zinc were below the recommended values. The iron intake fulfilled the recommendations except for the 2-year-olds and the 13-year-old girls. The intake of protein and fat expressed in per cent of the total energy intake was very similar in all age groups, about 14 per cent and 35-37 per cent respectively. The mean ratio between polyunsaturated and saturated fatty acids (P/S ratio) was also the same in all age groups, i.e. 0.22-0.23. This low ratio is explained by a high consumption of dairy products. Furthermore, the nutrient density of the food did not change appreciably with age. The only exception was found for the 2-year-old children, who had slightly higher nutrient density values on account of a relatively high consumption of fortified follow-up formula. In all age groups the mean nutrient densities of vitamins D and B6 and of iron were below the recommendations to varying degrees. No clinical signs of nutritional deficiencies, iron deficiency included, were found in any age group.(ABSTRACT TRUNCATED AT 400 WORDS)

  • 37. Hambraeus, L
    et al.
    Holmgren, G
    Samuelson, Gösta
    Dietary treatment of adult patients with phenylketonuria1971In: Nutrition and metabolism, ISSN 0029-6678, Vol. 13, no 5, p. 298-317Article in journal (Refereed)
  • 38. Hambraeus, L
    et al.
    Holmgren, G
    Samuelson, Gösta
    Ska äldre PKU-patienter behandlas?: [Should older patients with PKU be diet treated?].1974In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 71, no 12, p. 1183-4Article in journal (Refereed)
  • 39. Hedgran, M
    et al.
    Samuelson, Gösta
    Barnundersökningen 1980-811991In: Vår föda, ISSN 0042-2657, Vol. 43, no 1, p. 6-7Article in journal (Other academic)
  • 40. Hedgren, M
    et al.
    Arvidsson Lenner, R
    Samuelson, Gösta
    A dietary survey in adolescents: Methodological aspects of a 7-day food record1995In: Scandinavian Journal of Nutrition, ISSN 1102-6489, Vol. 39, no 2, p. 60-65Article in journal (Refereed)
  • 41. Hedgren, M
    et al.
    Samuelson, Gösta
    Sjukhuskost för barn och ungdom: En jämförelse mellan allmän kost och diabeteskost1991In: Näringsforskning, ISSN 0465-7675, Vol. 35, no 3, p. 111-115Article in journal (Other academic)
  • 42. Hellerud, C
    et al.
    Wramner, N
    Erikson, A
    Johansson, A
    Samuelson, Gösta
    Lindstedt, S
    Glycerol kinase deficiency: follow-up during 20 years, genetics, biochemistry and prognosis.2004In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 93, no 7, p. 911-21Article in journal (Refereed)
    Abstract [en]

    AIM: To follow two children with isolated glycerol kinase deficiency (GKD) with severe symptoms into adulthood.

    METHODS: The patients were followed during approximately 20 y and interviewed about symptoms, diet and physical activity. Fasting provocations, bicycle ergometer tests, dietary registrations, enzyme and mutation analysis were performed by standard protocols.

    RESULTS: The activity of glycerol kinase (GK) in fibroblasts was <10% of reference. One case had a deletion of exon 17, the other a mutation in exon 7 of the GK gene (601 A-->G). Both mothers were heterozygotes. Two maternal male cousins in one of the families were hemizygotes without symptoms. Tests performed in childhood documented pronounced sensitivity to fasting and physical exercise, whereas such tests at 23 and 31 y of age were essentially normal but with pronounced ketonaemia. After puberty, the boys had no hypoglycaemic symptoms and now report no problems with their condition; thus, their phenotype has changed over time.

    CONCLUSION: The greater importance of glycerol as a gluconeogenetic substrate in children than in adults may explain the episodes in young patients with GKD, often elicited by catabolic stress. With meals at frequent intervals, access to glucose and avoidance of strenuous sports, the prognosis is good for a normal adult life of a young child with isolated GKD and symptoms of hypoglycaemia.

  • 43. Hermansson, B
    et al.
    Holmgren, G
    Samuelson, Gösta
    Juvenile diabetes mellitus and atopy.1971In: Human Heredity, ISSN 0001-5652, E-ISSN 1423-0062, Vol. 21, no 5, p. 504-8Article in journal (Refereed)
  • 44. Holm, A K
    et al.
    Samuelson, Gösta
    Uhrbom, E
    [Dietary formulas for adults].1983In: Tandläkartidningen, ISSN 0039-6982, Vol. 75, no 8, p. 442-3Article in journal (Refereed)
  • 45. Holm, Ann-Karin
    et al.
    Samuelson, Gösta
    Kostrådgivning inom hälso- och tandhälsovård för barn: förslag till kostanemnesformulär1981In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, no 3, p. 151-152Article in journal (Other academic)
  • 46. Holmgren, G
    et al.
    Blomquist, H K
    Samuelson, Gösta
    Positive effect of a late introduced modified diet in an 8-year-old pku child.1980In: Neuropadiatrie, ISSN 0028-3797, Vol. 11, no 1, p. 76-9Article in journal (Refereed)
    Abstract [en]

    A modified low phenylalanine diet was instituted in an 8-year-old PKU boy earlier untreated and mentally retarded. The boy was treated during a ten year observation period. A marked progress in mental capacity and in IQ scoring was seen. The difficulties in objective evaluation of the benefit of late introduced treatment with a diet low in phenylalanine is discussed.

  • 47. Holmgren, G
    et al.
    Jeppson, J O
    Samuelson, Gösta
    High-voltage electrophoresis in urinary amino acid screening1970In: Scandinavian Journal of Clinical and Laboratory Investigation, ISSN 0036-5513, E-ISSN 1502-7686, Vol. 26, no 4, p. 313-318Article in journal (Refereed)
  • 48. Holmgren, G
    et al.
    Samuelson, Gösta
    Hermansson, B
    The prevalence of diabetes mellitus: a study of children and their relatives in a northern Swedish county.1974In: Clinical Genetics, ISSN 0009-9163, E-ISSN 1399-0004, Vol. 5, no 5, p. 465-8Article in journal (Refereed)
  • 49. Holmgren, G
    et al.
    Samuelson, Gösta
    Sjögren, S
    Treatment of a presymptomatic 14-year-old girl with Wilson's disease.1982In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 87, no 1, p. 91-6Article in journal (Refereed)
  • 50.
    Hoppe, Michael
    et al.
    Department of Gastroenterology and Hepatology , Clinical Nutrition Unit , Sahlgrenska University Hospital , Gothenburg , Sweden.
    Hulthén, Lena
    University of Gothenburg , Department of Internal Medicine and Clinical Nutrition , Sahlgrenska Academy , Gothenburg , Sweden.
    Samuelson, Gösta
    University West, Department of Health Sciences, Section for nursing - graduate level. Uppsala University , Department of Clinical Sciences/Clinical Physiology , Uppsala , Sweden..
    Is cord blood hepcidin influenced by the low-grade acute-phase response occurring during delivery?: A small-scale longitudinal study2019In: The Journal of Maternal-Fetal & Neonatal Medicine, ISSN 1476-7058, E-ISSN 1476-4954, Vol. 32, no 13, p. 2166-2172Article in journal (Refereed)
    Abstract [en]

    AIM: To measure serum hepcidin in late pregnancy and in cord blood, and to analyze relationship between hepcidin, interleukin-6 and biomarkers of fetal iron status.

    MATERIALS AND METHODS: Data from 15 uncomplicated singleton pregnancies were analyzed longitudinally in trimester 3 (T3) and at birth.

    RESULTS: In T3, S-ferritin (median 14 µg/L) and transferrin (median 4.0 g/L) indicated low iron status, whereas the median soluble transferrin receptor (sTfR) was 4.0 mg/L, ie within the reference interval. Median T3 S-hepcidin was 7.8 ng/mL. Later on in cord blood, ferritin concentration (180 µg/L) were significantly higher, transferrin concentration (1.8 g/L) were significantly lower, and both sTfR (4.7 mg/L) and S-hepcidin concentrations (30.5 ng/mL) were significantly higher than maternal T3 concentrations. At the same time, cord blood interleukin-6 indicated an activated acute-phase reaction. In T3, after logarithmic transformation, there was a significant correlation between S-hepcidin and both S-ferritin (r = 0.691) and sTfR (r = -0.825). There was also a significant correlation between S-ferritin and both sTfR (r = -0.729) and transferrin (r = 0.549) in T3.

    CONCLUSIONS: Although S-ferritin, S-hepcidin, and sTfR were correlated during pregnancy, these relationships were not apparent in umbilical cord blood. Further, cord blood interleukin-6 indicated an activated acute-phase response, and sTfR, which is known to be unaffected by inflammation, indicated a low iron status in cord blood. Thus, instead of representing an enhanced iron status, the data appear to suggest that hepcidin and ferritin in cord blood may be influenced by the low-grade acute-phase response that occurs during delivery.

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