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  • 1.
    Berntsson, Shala Ghaderi
    et al.
    Uppsala University, Department of Neuroscience, Neurology, University Hospital, Uppsala, Sweden.
    Landtblom, Anne-Marie
    Uppsala University, Department of Neuroscience, Neurology, University Hospital, Uppsala, Sweden, Department of Clinical and Experimental Medicine, Neurology, Medical Faculty, University of Linköping, Linköping, Sweden.
    Flensner, Gullvi
    University West, Department of Health Sciences, Section for nursing - graduate level.
    Cerebellar ataxia and intrathecal baclofen therapy: Focus on patients´ experiences2017In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 2, no 6, article id e0180054Article in journal (Refereed)
    Abstract [en]

    Elucidating patients´ experiences of living with chronic progressive hereditary ataxia and the symptomatic treatment with intrathecal baclofen (ITB) is the objective of the current study. A multicenter qualitative study with four patients included due to the rare combination of hereditary ataxia and ITB therapy was designed to elucidate participants' experiences through semi-structured interviews. The transcribed text was analyzed according to content analysis guidelines. Overall we identified living in the present/ taking one day at a time as the main theme covering the following categories: 1) Uncertainty about the future as a consequence of living with a hereditary disease; The disease; 2) Impact on life as a whole, 3) Influence on personal life in terms of feeling forced to terminate employment, 4) Limiting daily activities, and 5) ITB therapy, advantages, and disadvantages. Uncertainty about the future was the category that affected participants' personal life, employment, and daily activities. The participants' experience of receiving ITB therapy was expressed in terms of improved quality of life due to better body position and movement as well as better sleep and pain relief.

  • 2.
    Gauffin, Helena
    et al.
    Linköping University, Department of Neurology and Department of Clinical and Experimental Medicine, Linköping, Sweden.
    Flensner, Gullvi
    University West, Department of Nursing, Health and Culture, Division of Advanced Nursing.
    Landtblom, Anne-Marie
    Uppsala University, Department of Neuroscience, Uppsala, Sweden.
    Being parents with epilepsy: thoughts on its consequences and difficulties affecting their children2015In: Neuropsychiatric Disease and Treatment, ISSN 1176-6328, E-ISSN 1178-2021, Vol. 11, p. 1291-1298, article id NDT.S74222Article in journal (Refereed)
    Abstract [en]

    Objective: Parents with epilepsy can be concerned about the consequences of epilepsy affecting their children. The aim of this paper is to describe aspects of what it means being a parent having epilepsy, focusing the parents’ perspectives and their thoughts on having children.

    Methods:

    Fourteen adults aged 18–35 years with epilepsy and subjective memory decline took part in focus-group interviews. The interviews were conducted according to a semi-structured guideline. Material containing aspects of parenthood was extracted from the original interviews and a secondary analysis was done according to a content-analysis guideline. Interviews with two parents for the Swedish book Leva med epilepsi [To live with epilepsy] by AM Landtblom (Stockholm: Bilda ide; 2009) were analyzed according to the same method.

    Results:

    Four themes emerged: (1) a persistent feeling of insecurity, since a seizure can occur at any time and the child could be hurt; (2) a feeling of inadequacy – of not being able to take full responsibility for one’s child; (3) acknowledgment that one’s children are forced to take more responsibility than other children do; and (4) a feeling of guilt – of not being able to fulfill one’s expectations of being the parent one would like to be.

    Conclusion:

    The parents with epilepsy are deeply concerned about how epilepsy affects the lives of their children. These parents are always aware that a seizure may occur and reflect on how this can affect their child. They try to foresee possible dangerous situations and prevent them. These parents were sad that they could not always take full responsibility for their child and could not live up to their own expectations of parenthood. Supportive programs may be of importance since fear for the safety of the child increases the psychosocial burden of epilepsy. There were also a few parents who did not acknowledge the safety issue of their child – the authors believe that it is important to identify these parents and provide extra information and support to them.

  • 3.
    Lagrosen, Yvonne
    et al.
    University West, Department of Engineering Science, Division of Process and Product Development.
    Travis, Frederick T.
    Maharishi University of Management, Center for Brain, Consciousness and Cognition, Fairfield, IN, United States.
    Exploring the connection between quality management and brain functioning2015In: The TQM Journal, ISSN 1754-2731, E-ISSN 1754-274X, Vol. 27, no 5, p. 565-575Article in journal (Refereed)
    Abstract [en]

    Purpose: The purpose of this paper is to explore possible connections between brain functioning and quality management. Design/methodology/approach: Five central principles regarding brain functioning according to neuroscience are conceptually described and related to principles and major concepts in quality management with a special emphasis on Deming’s system of profound knowledge. Findings: The principles are shown to be related in a profound way. The first principle of coherence is closely related to appreciation for a system. The principle of homeostatic feedback loops concerns events that disturb the equilibrium of a system and is related to knowledge about variation. Neural plasticity is related to a theory of knowledge. The last two principles involve emotional and cognitive contributions to decision-making. They are closely related to the element psychology and one of them could lead to a further development of Deming’s system of profound knowledge. Research limitations/implications: The paper adds to the understanding of the role brain integration has for success in quality management efforts. A limitation is that it is difficult to localise higher-order thinking in brain function. Nonetheless, the research is indicative and provocative as a window to stimulate research into the fundamental basis of quality management success. Practical implications: The findings provide a deeper understanding of profound knowledge in quality management through relating it to how the brain is functioning, which is of value for quality managers and leaders striving for excellence for their organisations. Originality/value: The connection of brain principles with Deming’s profound knowledge has not been elaborated in the literature before. © Emerald Group Publishing Limited.

  • 4.
    Landry, M.
    et al.
    University of Bordeaux, IINS, CNRS UMR 5297, Bordeaux, France.
    Bouchatta, O.
    Cadi Ayyad University, LPNB URAC 37, Marrakesh, Morocco.
    M’Hamed, S. B.
    Cadi Ayyad University, LPNB URAC 37, Marrakesh, Morocco.
    Bouali-Benazzouz, R.
    University of Bordeaux, IINS, CNRS UMR 5297, Bordeaux, France.
    Kerekes, Nora
    University West, Department of Health Sciences, Section for health promotion and care sciences.
    Fossat, P.
    University of Bordeaux, IINS, CNRS UMR 5297, Bordeaux, France.
    Bennis, M.
    Cadi Ayyad University, LPNB URAC 37, Marrakesh, Morocco.
    Mechanisms of pain hypersensitivity in a pharmacological mouse model of attention-deficit/hyperactivity disorder2017In: Journal of Neurochemistry, ISSN 0022-3042, E-ISSN 1471-4159, Vol. 142, no 1, SI, article id WTH13-07Article in journal (Refereed)
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