Background: Multiple sclerosis (MS) is a serious chronic disease that affects people all over the world. In Sweden about a thousand new patients every year got MS, and today there are approximately 17 500 people who have the diagnosis. As MS often arise in the prime time of life and is unpredictable this causes great difficulty for those individuals who are diagnosed and then forced to live with the disease. Aim: The aim of the study was to illuminate patients' experience of living with Multiple Sclerocis. Method: Method was a literature-based study, in which the analysis is based on qualitative studies. Results: The result showed that MS have a great influence in patients life and tell us how patients experience emotions fear, despair, uncertainty and hope in their everyday lives and emotions of fear. Conclusion: It is evident from the findings of this study that individuals living with MS face several challenges in life. It is valuable for nurses and people who work in health care to know how these patients experience their daily lives. This study will hopefully create awareness of the disease and how the patients feel.