Background: Currently it is a stream of refugees; one of the history´s greatest, and many refugees are coming to Sweden that affects the healthcare. For nurses it is important to have an understanding of different cultures as well as handle different situations in the right way. It is important that every individual receives the care they need and does not get affected by cultural factors. The patients should be treated with respect and the nurses should indicate safety on any level. Aim: To describe factors that affects the meetings between nurse and patient with different cultural backgrounds. Method: A literature study was accomplished based on analysis made by Qualitative and Quantitative articles. Results: The study resulted in two main themes. The first, which is the importance of communication in a meeting and the second is the competences within culture for the nurse in health care. In cross-cultural-meetings the communication is important otherwise there is a risk the caring will not be as good as it can be. Four subthemes showed a finding about how language-barriers can contribute to misunderstandings with more analysis and samplings as a consequence and the need of a professional interpreter. There also was the importance of the need of knowledge about culture diversities and methods to support the nurse in giving good care. The fourth subtheme is about that there are culture diversities in cross-cultural-meeting. Conclusion: The result shows that the significant factor when meetings occur is the lack of communication. For promotion of good healthcare through a respectable meeting, it is necessary to be aware of the importance of a professional interpreter. The result also shows that cultural differences occur and a need for interpreter guidance when necessary is needed to avoid misunderstandings. With good knowledge in the issue the nurses will have better conditions for the meetings with the patients with different cultural backgrounds.