Background: The nursing of patients who require isolation means to meet and care for people and their families in a vulnerable situation. It is important to gain insight into patients' experience to get a better understanding of source isolation. Increased knowledge provides better conditions for the staff to respond to patients in isolation.

Aim: The aim of this study was to describe patients' experience of isolation in hospital care. Method: A literature review based on previous research. Nine articles were selected, four with qualitative approach, three with quantitative approach and two with mixed design i.e. both qualitative and quantitative approach.

Results: The study resulted in five categories that reflected patients' experience of isolation in hospital care. Conclusion: The aim was to describe patients' experience of isolation in hospital care. We performed a literature review and came up with five categories: To be marked, Frustration due to lack of understanding, Fear and anxiety, Loneliness and confinement and Satisfaction with health care. Our result show that many patients experience negatively charged emotions while in isolation, but even so, they are not less satisfied with the care compared to nonisolated patients. Comprehension for the impact of isolation on patients' emotional wellbeing can improve the nursing for these patients. "To isolate the disease - not the patient" ought to be the motto for the nurse and the rest of the team involved in the care for the isolated patient.