Titanium and titanium alloys are of great interest in aerospace and medical industries. Especially, Ti-6Al-4V alloys show a unique combination of high mechanical strength, low density and an outstanding corrosion resistance. However, particularly the high strength restricts industrial processing procedures. Thus, there are increasing demands for powder metallurgical process routes. For pure titanium, cold spraying already proved to be a promising alternative for manufacturing semi-finished products, mainly due to the use of high process gas temperatures and pressures. Nevertheless, due to the higher material strength, the production of Ti-6Al-4V coatings by cold spraying is still challenging, even under higher process parameters. The present study deals with the production and characterization of Ti-6Al-4V coatings produced by cold spraying. All experiments were performed using nitrogen as process gas. By a systematic variation of the spray parameters up to a process gas temperature of 1000°C and a process gas pressure of 5 MPa, the coatings could be tuned for optimum mechanical properties. In addition, attainable coating properties are described in terms of a newly introduced coating quality parameter η, namely the ratio of the particle velocity to the critical velocity, to reveal the most significant influences on coating performance and to give hints for further optimization.