The concept of information is often taken for more or less granted in research about information systems. This paper introduce a model starting with Shannon and Weaver’s data transmission model and ends with knowledge transfer between individual persons. The model is in fact an enhanced communication model giving a framework for discussing problems in the communication process. A specific feature of the model is the aim for providing design guidelines in designing the communication process. The article ends with identifying a need for develop the model further to incorporate also communication within and between organisations of different kinds.