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Interpretation of subjective symptoms in double-blind placebo-controlled food challenges - interobserver reliability
University West, Department of Economics and IT.ORCID iD: 0000-0002-0575-4309
Sahlgrenska University Hospital, Department of Respiratory Medicine and Allergy.
University West, Department of Economics and Informatics.
Karolinska Institute, Institute of Environmental Medicine.
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2004 (English)In: Allergy. European Journal of Allergy and Clinical Immunology, ISSN 0105-4538, E-ISSN 1398-9995, Vol. 59, no 3, p. 354-6Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Subjective symptoms after food challenges are difficult to interpret and no standard is available. We discuss a strategy for how to interpret a diary. Furthermore, the interobserver reliability is evaluated. METHODS: Diaries for 32 patients with subjective symptoms were used. The diaries were re-evaluated with a predefined strategy by three independent observers. RESULTS: The proportion of positives was 21.9% among the old diagnoses, according to the new approach 34.4% (observers I and II) and 37.5% (observer III) were positive. The new approach had high interobserver reliability (97 and 100%). CONCLUSIONS: The proportion of positives depends on how subjective symptoms are interpreted. Interpretations of subjective symptoms in diaries could be made with high interobserver reliability.

Place, publisher, year, edition, pages
2004. Vol. 59, no 3, p. 354-6
Keywords [en]
double-blind placebo-controlled food, challenge; diagnosis, food allergy, food intolerance, subjective symptoms
National Category
Pharmacology and Toxicology Nursing
Research subject
NURSING AND PUBLIC HEALTH SCIENCE, Nursing science
Identifiers
URN: urn:nbn:se:hv:diva-1757DOI: 10.1111/j.1398-9995.2003.00437.xPubMedID: 14982520OAI: oai:DiVA.org:hv-1757DiVA, id: diva2:241932
Available from: 2009-10-06 Created: 2009-10-02 Last updated: 2018-01-13Bibliographically approved

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Gellerstedt, Martin

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CiteExportLink to record
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