Vaccination as a part of the preventative public health project has for many years been one of the important tasks of the children's health care. The vaccination program has been adjusted to current research and the health situation in the country. Having their children vaccinated is not something obvious for all parents, though. Especially the vaccination against measles, whooping cough and German measles have been questioned. The purpose of this literature study was to investigate the reasons for the resistance to vaccinate and to illuminate the security creating advice of the nurse at the public health centre. The study showed that there were varying ways to look at the MPR-vaccination among the parents. It could be considered as something injuring while childhood illnesses were sometimes considered as something positive. The social circumstances and a lack of trust were also factors that influenced the parents. It was also obvious that the parents need a district nurse that is a good listener and who can give advice individually and also give information that creates security. This information consists of telling the parents that the MPR-vaccine does not cause autism or chronic intestine disease. Furthermore, there is a need to inform of the illnesses and their risks. This information is objectively given by a well informed nurse, whose task it is to work for a vaccination program with the widest coverage possible.