Current demographic trends, characterized by an aging population and the prevalence of chronic illnesses, pose significant challenges for healthcare in Sweden and globally. Digital health, including patient self-monitoring of health data, is acknowledged as a promising approach to address these issues. However, self-monitoring also presents various socio-technical challenges from the perspective of healthcare professionals, as the integration of technology influences work tasks, professional roles, and clinical interactions. This case study examines the introduction of self-monitoring within the Swedish healthcare context, specifically focusing on the role of digitalization coordinators and their perceptions and insights regarding the integration of self-monitoring into daily clinical practice. The study identifies critical challenges and suggests solutions. First, it highlights the impact of self-monitoring on professional identity and patient interactions, emphasizing that balancing technology and personal contact is essential to ensure quality care and patient outcomes. Secondly, it also addresses issues related to perceived complexity, resistance to technology, and resistance to change, emphasizing the importance of education and stakeholder engagement to facilitate awareness, enhance staff’s technological proficiency, and improve healthcare outcomes. In conclusion, findings from this study contribute to understanding the implementation of self-monitoring in Swedish healthcare and highlight the importance of preserving the human element in healthcare while leveraging the benefits of technology