Extensive studies have been carried out on the relationship between sustainability and profitability, which has resulted in varying results. However, majority of studies have positive relationships, indicating that by adopting a more sustainable strategy, companies can benefit in the long run. The study aims to increase understanding of the connection between profitability and sustainability and identify differences between the three dimensions of ESG: environment, social and governance.Another purpose is to attempt to find and if there are changes in sustainability efforts after the Paris Agreement. The study analyzed American public companies in different industries during 2010-2021. The data is retrieved from Refinitiv Eikon, and the observations are tested by running a multiple linear regression with fixed effect. The results from the regression did not show any positive relationship between sustainability and profitability. On the contrary, most of them are negative. However, none of the results are statistically significant, with low indications that the dependent variable could be explained by the independent variables.