The paper focuses on the submerged arc welding (SAW) process in application to structures for Arctic conditions. One of the technical challenges for modern Arctic structures is to produce high-quality welds since a weld is usually the weakest part of any structure. Welding is especially difficult for the high strength steels (HSS), which are used in structures for weight-reduction purposes. The objective of the study is to explore the usability, development possibilities and parameters of SAW process for welding of thick cold-resistant HSS plates. Meeting this objective required in-depth understanding of the welding and material science background, which includes the quality requirements of weld joints intended for Arctic service as described in various standards, properties of cold-resistant HSS and description of testing methods used to validate welding joints for low temperature conditions. The study describes experimental findings that improve understanding of SAW process of thick quenched and tempered (QT) and thermo-mechanically processed (TMCP) HSS plates. Experiments were conducted to develop SAW procedures to weld several thick (exceeding 25 mm) high strengths (580–650 MPa tensile strength) cold-resistant (intended operational temperature at least −40 ℃) steel grades. The welds were evaluated by a wide range of industrial tests: analyses of chemical, microstructural and mechanical properties; hardness tests; and cold resistance evaluation tests: the Charpy V-notch impact test and the Crack tip opening displacement (CTOD) test. Acceptable welding parameters and recommendations were developed, and the results of the experiments show that high quality welds can be obtained using heat input up to 3.5 kJ/mm.