Domestic violence is the act of violence from a family member or partner. Domestic violence counts as a social issue that one of three women globally and one of four women in Sweden has experienced. Violence can be expressed in different ways and science has revealed that women have a higher risk than men of being victims of domestic violence. Women who endure violence usually do not show any obvious signs and therefore it is of importance to ask the question about domestic violence to all female patients. Nurses need knowledge about symptoms and signs of violence in order be able to detect these women. Even though the nurses carry the responsibility of asking female patients about domestic violence, most of the time nurses do not ask. The aim of this study was to shed light on the nurse's experience of asking female patients about domestic violence. This qualitative based literary study includes eleven articles. The results of this study show that nurses want to help women who live with domestic violence, but the subject is perceived as uncomfortable which makes asking the question more difficult. Nurses experience the heavy workload and the hospital environment as barriers to asking the question during the right conditions. Nurses expressed feelings of ambiguity as to who was responsible for handling the issue and saw that as a barrier to asking the question. For more women to have the opportunity to get adequate help, nurses need to receive further training and knowledge about domestic violence.