The embedding of digital platforms into professional practice has changed how people collaborate, learn and share knowledge at work. The healthcare sector provides an illustrative case for developments in this area. Through the introduction of a virtual collaboration platform in a continuing professional development program for pediatricians, this interdisciplinary research aims to promote continuity of the educational outcomes along with a better understanding of the usefulness of virtual collaboration and knowledge sharing at work. The research question is: How do pediatricians co-design and use a virtual collaboration platform for knowledge sharing and learning in action? The method is participatory action research, in which participants were co-designers of the content that was developed. The paper outlines some of the benefits and challenges currently emerging from the integration and use of virtual collaborations in clinical practice and provides design considerations on how to co-design content to use in virtual collaboration.