We present ongoing work on the design of an information system for users with reading disabilities and users with reduced vision. The design target is a portable, auditory, location-aware information system, to complement visually displayed information in exhibitions. Applying a user-centered, we identify non-typical user-groups’ specific requirements, which are turned into a design. The first design-iteration, which includes a formative evaluation, using a mock-up prototype, with dyslectic and visually impaired participants, is completed. The evaluation indicates that the user-group’s specific aspects we have identified are relevant, while designing for these groups. © 2006, by Walter de Gruyter GmbH & Co. All rights reserved.