Background: Person-centered care sciences are experiencing rapid progress. Personalization in care services is becoming the norm, and implementation from scientific knowledge is increasingly acknowledged and mandated. Advances in personality and brain disorder research are crucial in assisting the future development of personalized care. Aim: We will attempt to present glimpses into the future of personalized care with support from frontline science, measurement, and practice, updating with input from personality genetics and measurement theory. Outline: We present three broad developments: (1) scientific advancements in understanding how personality and genetics are central in predicting mental health and disorders, with the potential to increase predictive diagnosis and treatment validity; (2) measurement advancements with help of trait dimensions and latent structures, with the potential to increase reliability in assessing personalized care needs and functioning; (3) practical advancements in implementing a personalized approach in care services, with the potential to increase effectiveness and satisfaction with patients. We review this glimpse into the future by referencing key findings in personality and assessment meta-analyses, genome-wide association studies (GWAS), and trait measurements in psychiatric disorders. Conclusion: Personalizing care services will benefit practitioners and patients. We suggest and recommend that personalized care diagnosis and treatment is the way forward and that the future will be potentially revolutionized by incorporating the presented advancements in personality research and brain sciences.