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Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation
Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
KU Leuven – University of Leuven, KU Leuven Department of Public Health and Primary Care, Leuven, Belgium; University of Gothenburg, Institute of Health and Care Sciences, Gothenburg, Sweden; University of Cape Town, Department of Paediatrics and Child Health, Cape Town, South Africa.
University of Toronto, Peter Munk Cardiac Centre, University Health Network,Toronto, Canada; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon, USA.
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2019 (English)In: American Journal of Cardiology, ISSN 0002-9149, E-ISSN 1879-1913, Vol. 124, no 1, p. 144-150Article in journal (Refereed) Published
Abstract [en]

Patients with a Fontan circulation are at risk of a sedentary lifestyle. Given the direct relationship between physical activity and health, promotion of physical activity has the potential to improve outcomes, including quality of life (QOL). This study aimed to describe self-reported physical activity levels in adult Fontan patients and examine associations between physical activity, perceived health status and QOL. The sample consisted of 177 Fontan patients (Mage = 27.5 ± 7.6 years, 52% male) who reported their physical activity, perceived health status, and QOL as part of the cross-sectional Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease - International Study. Descriptive statistics and univariate analyses of variance with planned contrasts were computed to describe physical activity characteristics. Mediation analyses tested whether perceived health status variables mediated the association between physical activity and QOL. Forty-six percent of patients were sedentary while only 40% met international physical activity guidelines. Higher physical activity was associated with younger age, lower NYHA class, higher perceived general health, and greater QOL. Patients who commuted by walking and engaged in sports reported better perceived health and QOL. Mediation analyses revealed that perceived general health but not NYHA functional class mediated the association between physical activity and QOL (αβ = 0.22, 95% confidence interval = 0.04 to 0.49). In conclusion, Fontan patients likely benefit from regular physical activity, having both higher perceived general health and functional capacity; greater perceived health status may contribute to enhanced QOL. In conclusion, these data support the pivotal role of regular physical activity for Fontan patients.

Place, publisher, year, edition, pages
2019. Vol. 124, no 1, p. 144-150
Keywords [en]
quality of life, fontan circulation, physical activity
National Category
Nursing
Research subject
NURSING AND PUBLIC HEALTH SCIENCE, Nursing science
Identifiers
URN: urn:nbn:se:hv:diva-13842DOI: 10.1016/j.amjcard.2019.03.039ISI: 000474328300021PubMedID: 31030969Scopus ID: 2-s2.0-85064899686OAI: oai:DiVA.org:hv-13842DiVA, id: diva2:1317957
Funder
Swedish Heart Lung Foundation, 20130607
Note

Funders: KU Leuven (OT/11/033); Cardiac Children's Foundation Taiwan: Taipei, Taiwan (CCF2013_02);

Available from: 2019-05-24 Created: 2019-05-24 Last updated: 2019-10-18Bibliographically approved

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