Nowadays, automatization is the need of industries because of its variety of products and demands in the market. The industries which are dependent on this automatization are facing var-ious problems such as vendor and platform dependency of devices, data security and modifica-tion cost of existing systems. The industrial communication protocols play an important role in all above situations. Considering all these factors which are affecting the cost and time of production, the community of researchers and engineers along with the coordination of German government introduced the OPC-UA communication protocol. The OPC-UA communication protocol is known as one of the pillars of smart industrialization i.e. Industry 4.0. To testify the OPC-UA compliance, the simulation of the control systems is designed and implemented. The robot cell is considered where communication channel between the robot and PLC is created using OPC-UA. The robot performs the tasks on the given instructions by the PLC through HMI. As OPC-UA protocol model is also known as server-client architecture, the cell PLC is considered as server and the robot simulated in the RobotStudio is considered as client. However, the OPC UA client application is considered as master PLC which contains the main control HMI. For the simulation, the CODESYS demo SoftPLC controller, Visual studio 2015 with .NET SDK and RobotStudio 6.06 with PC SDK is used. The communication between the two OPC UA client applications and one OPC UA SoftPLC server is in the string data format.