The paper describes the investigations of mechanical properties of various zirconia coatings having different microstructure, phase content and chemical composition. The coatings were deposited using Suspension Plasma Spraying technology. The suspensions were formulated using three different powders: (i) ZrO2 + 8 wt.% Y2O3 (ii) ZrO2 + 14 wt.% of Y2O3 and (iii) ZrO2 + 24 wt.% of CeO2 + 2.5 wt.% of Y2O3. Moreover, three different plasma torches were to spray: (i) SG-100 of Praxair; (ii) Axial III of Mettech and (iii) hybrid Water-Stabilized Plasma torch of IPP Prague. The coatings had different microstructures: a columnar-like and a two-zone-microstructure. The analysis of mechanical properties was performed using instrumented indentation technique (NT) using a multi-cyclic loading to obtain the in-depth variation of the mechanical properties. The hardness (H) and Young’s modulus (E) of coatings were found out. The measurements were made on the surface of coatings. The influence of the coating morphology on their mechanical properties was researched and discussed.