Amyotrophic Lateral Sclerosis (ALS) is a serious disease in which the nerves that control muscles gradually breaks down. There is still no known cure for the disease that has a fatal outcome. ALS is a disease that causes a great deal of suffering for the people who have the disease and their surroundings. 

The aim of this study was to investigate how quality of life is experienced by people with ALS.

This study used a systematic literature-based method with qualitative approach. Searches were made in the databases Cinahl and PubMed and were then examined on the basis of a review template. Nine qualitative articles were selected for the result.

The result shows that people suffering from ALS can experience quality of life. The most important factors to experience quality of life were the internal and external factors. One of the internal factors was described as hope, which helps the person with ALS believe that something good will happen. The external factor indicate support from the surroundings, such as family and nurse.

It is important that nurses are aware of the fact that people with ALS experience quality of lifeby highlighting the needs and desires that improve quality of life.