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A longitudinal study of iron status in healthy Danish infants: effects of early iron status, growth velocity and dietary factors.
1995 (engelsk)Inngår i: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 84, nr 9, s. 1035-44Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

In a cohort of term infants (n=91), followed from birth to 12 months, iron intake was examined by 24-h food records, and iron status by blood samples (haemoglobin (Hb)), mean corpuscular volume (MCV), serum values for iron, ferritin and transferrin, and erythrocyte protoporphyrin) at 2, 6 and 9 months. At 9 months of age, 5% had anaemia (Hb<105 g/l), but none had developed iron deficiency according to strict definitions used in this study (serum ferritin < 13 micrograms/l and transferrin saturation < 10%). Infants with high serum ferritin, serum transferrin and erythrocyte protoporphyrin values at one blood sampling also had high values at the following sample (tracking, r=0.45-0.80), suggesting that iron stores at delivery are an important determinant of iron stores during late infancy. Factors related to changes in serum ferritin were investigated by multiple linear regression. From 2 to 6 months, serum ferritin was negatively associated with knee-heel growth velocity (p=0.006) and positively with intake of infant formula (p=0.04). From 6 to 9 months it was negatively associated with intake of bread (p=0.001), and there was a trend for a positive association with intake of meat (p=0.07) and fish (p=0.08) and for a negative association with intake of cow's milk (p=0.07). In conclusion, those with a high growth velocity and a dietary pattern with a high intake of bread and a low intake of meat and fish had lower ferritin values and thereby an increased risk of depleting their iron stores later during infancy.

sted, utgiver, år, opplag, sider
1995. Vol. 84, nr 9, s. 1035-44
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URN: urn:nbn:se:hv:diva-13318PubMedID: 8652956OAI: oai:DiVA.org:hv-13318DiVA, id: diva2:1273788
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Professor Gösta Samuelson samlade trycksaker; 174

Tilgjengelig fra: 2018-12-21 Laget: 2018-12-21 Sist oppdatert: 2019-04-17bibliografisk kontrollert

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