There have been many studies and theories to prove the connection or relationship that exists between the flow of investment and the growth of the economy of a country. This study aimed at examining the impact Foreign Direct Investment has on the economic growth of Sub-Saharan Africa from 1999 to 2019. Using Panel data analysis, we analysed the impact on thirty-Five selected countries in this region. Based on empirical studies and theories, we researched using carefully selected variables with data sourced mainly from World Bank Development Indicators, World Governance Indicators as well as Data Stream. These variables include inflation that was realized to harm growth, contrary to human capital, financial market development, exchange rate, control of corruption as well as the openness of the economy were variables that were included in our study to analyse their relationship with economic growth. The findings were conclusive that FDI impact on growth is positive yet statistically insignificant to the economic growth of Sub-Saharan Africa.